Reza Momenan, PhD, Acting Chief
Section on Brain Electrophysiology and Imaging, LCTS

National Institute on Alcohol Abuse and Alcoholism
National Institutes of Health
10 Center Drive, Room 10-CRC/1E-5330: MSC 1108
Bethesda MD 20892-1108

Telephone: 301.451.6972
reza.momenan@mail.nih.gov

 

What we do

This section conducts both functional and structural brain imaging studies related to alcoholism. For functional work we primarily use functional magnetic resonance imaging (fMRI) techniques although positron emission tomographic (PET) studies are also undertaken. Structural studies include both measurements of brain volumes using MRI as well as diffusion tensor imaging (DTI). We also use nuclear magnetic resonance (NMR) spectroscopy to measure various brain metabolites. Recently much of our functional work has focused on emotion and motivation as they related to substance abuse. Pharmacological fMRI studies are also employed, particularly studies involving alcohol administration.


Current staff
 

Photo of Reza Momenan Reza Momenan, PhD
Acting Chief and Staff Scientist
telephone: 301.451.6972
reza.momenan@mail.nih.gov

Dr. Momenan provides research expertise and support in the areas of experimental design, imaging, and analysis to the SBEI and the Laboratory of Clinical and Translational Studies. He also conducts imaging research in both human and animal brain using various methods. His main focus of research is design and developing experiments utilizing various MR modalities for study of motivation, impulsivity, and emotions as related to addiction.

Photo of Dan Rio Dan Rio, PhD
Physicist/Mathematician
telephone: 301.402.2994
dan.rio@mail.nih.gov

Dr. Rio is a physicist/mathematician who setup the original imaging facilities in this section. His current interest is developing new models for analysis of functional MRI in addition to providing support in the areas of computational mathematics, mathematical modeling, image processing and experimental design.

  Erica Grodin
telephone: 301.451.6978

erica.grodin@nih.gov
Photo of Mike Kerich Mike Kerich
Computer Program Specialist
telephone: 301.496.6540
mike.kerich@mail.nih.gov

Mike Kerich is responsible for providing programming and technical support for the imaging research as well as backing up and maintaining several large servers for imaging data. He also provides desktop support for local users.

  Karan Mathur
telephone: 301.827.0321

karan.mathur@nih.gov
Photo of Betsy Davis Betsy Davis
Psychology Technician
telephone: 301.435.3493
betsy.davis@mail.nih.gov

Ms. Davis provides technical support for a variety of studies in the Section and the Laboratory.  She has worked on pre-processing of structural MRI images and training of staff in these methods.  She is currently working on the programming of data collection instruments for subjects, as well as acting as data monitor for several ongoing studies.

Photo of Xi Zhu Xi Zhu, PhD
Post-Doctoral IRTA
Photo of Rabina Joshi Rabina Joshi, BS
Post-Bacc IRTA

 

BEI Clinical Protocols

04-AA-0060   The Effect of Ethanol on Cerebral Blood Flow as Measured by Functional Magnetic Resonance Imaging and the Development of Conditioned Response to Ethanol Administration

03-AA-0013   Brain Activation in Response to Motivational and Affective Stimuli: Pharmacologist Manipulations

98-AA-0009   Screening Evaluation for NIAAA Protocols

98-AA-0056   Functional Neuroanatomy of Positive and Negative Affect in Alcoholics and Nonalcoholics
 

NIAAA Clinical Protocols & link to all NIH Clinical Protocols


Selected Publications

ORIGINAL PUBLICATIONS
 

Bjork JM, Chen G, Smith AR, Hommer DW: Incentive-elicited mesolimbic activation in adolescents with externalizing disorders. Journal of Child Psychology & Psychiatry. 2010 Jul 11;51(7):827-37.  PubMed

Gilman JM, Davis MB, Hommer DW: Greater activation in left hemisphere language–related regions during simple judgment tasks among substance-dependent patients in treatment for alcoholism. Alcoholism: Clinical and Experimental Research. 2010 Feb;34(2):331–41. PubMed

Bjork JM, Momenan R, and Hommer DW: Delay discounting correlates with proportional lateral frontal cortex volumes. Biological Psychiatry. 2009 Apr 15;65(8):710-3. PubMed

Bjork JM, Smith AR, Hommer DW: Striatal sensitivity to reward deliveries and omissions in substance dependent patients, NeuroImage. 2008 Oct 1;42(4):1609-21. PubMed

Gilman JM, Hommer DW. Modulation of brain response to emotional images by alcohol cues in alcohol-dependent patients. Addiction Biology. 2008 Sep;13(3-4):423-34. PubMed

Bjork JM, Knutson B, Hommer DW: Incentive-elicited striatal activation in adolescent children of alcoholics. Addiction. 2008 Aug;103(8):1308-19. PubMed

Bjork JM, Momenan R, Smith A, Hommer DW. Reduced posterior mesofrontal cortex activation by risky rewards in substance-dependent patients. Alcohol and Drug Dependence. 2008 May 1;95(1-2):115-28. PubMed

Gilman JM, Ramchandani VA , Davis MB , Bjork JM, Hommer DW. Why we like to drink: An fMRI Study of the Rewarding and Anxiolytic Effects of Alcohol. Journal of Neuroscience. 2008 Apr 30;28(18):4583-91. PubMed

George DT, Gilman J, Hersh J, Thorsell A, Herion D, Geyer C, Peng X, Kielbasa W, Rawlings R, Brandt J, Gehlert DR, Tauscher JT, Hunt SP, Hommer D, Heilig M. Neurokinin 1 receptor antagonism as a possible therapy for alcoholism. Science. 2008 Mar 14;319(5869):1536-9. PubMed

Gilman JM, Bjork JM, Hommer DW. Parental alcohol use and brain volumes in early- and late-onset alcoholics. Biological Psychiatry. 2007 Sep 15;62(6):607-15. PubMed

Salloum JB, Ramchandani VA, Bodurka J, Rawlings R, Momenan R, George D, Hommer DW. Blunted rostral anterior cingulate response during a simplified decoding task of negative facial expressions in alcoholic patients. Alcoholism: Clinical and Experimental Research. 2007 Sep;31(9):1490-504. PubMed

Schottenbauer MA, Hommer D, Weingartner H. Memory deficits among alcoholics: Performance on a selective reminding task. Aging, Neuropsychology, and Cognition. 2007 Sep;14(5):505-516. PubMed

Bjork JM, Smith A, Danube C, Hommer DW. Developmental differences in posterior mesofrontal cortex recruitment by risky rewards. Journal of Neuroscience. 2007 May 2;27(18):4839-49. PubMed

Schottenbauer MA, Momenan R, Kerich M, Hommer DW. Relationships among aging, IQ, and intracranial volume in alcoholics and control subjects. Neuropsychology. 2007 May;21(3):337-45. PubMed

Bjork JM, Hommer DW. Anticipating instrumentally obtained and passively-received rewards: A factorial fMRI investigation. Behavioural Brain Research. 2007 Feb 12;177(1):165-70. PubMed

Brown AK, George DT, Fujita M, Liow J, Ghose S, Sangare J, Hommer DW, Innis RB. PET [11C]DASB imaging of serotonin transporters in patients with alcoholism. Alcoholism: Clinical and Experimental Research. 2007 Jan;31(1):28-32. PubMed

Rio DE, Rawlings RR, Woltz LA, Salloum JB, Hommer DW. Single subject image analysis using complex general linear model - An application to functional magnetic imaging with multiple inputs. Computer Methods and Programs in Biomedicine. 2006 Apr;82(1):10-9. PubMed

Bjork JM, Hommer DW, Grant SJ, Danube C. Impulsivity in abstinent alcohol-dependent patients: relation to control subjects and type 1-/type 2-like traits. Alcohol. 2004 Oct-Nov;34(2-3):133-50. PubMed

Knutson B, Bjork JM, Fong GW, Hommer D, Mattay VS, Weinberger DR. Amphetamine modulates human incentive processing. Neuron. 2004 Jul 22;43(2):261-9. PubMed

Momenan R, Rawlings R, Fong G, Knutson B, Hommer D. Voxel-based homogeneity probability maps of gray matter in groups: assessing the reliability of functional effects. Neuroimage. 2004 Mar;21(3):965-72. PubMed

Bjork JM, Knutson B, Fong GW, Caggiano DM, Bennett SM, Hommer DW. Incentive-elicited brain activation in adolescents: similarities and differences from young adults. J Neurosci. 2004 Feb;24(8):1793-802. PubMed

Bjork JM, Grant SJ, Hommer DW. Cross-sectional volumetric analysis of brain atrophy in alcohol dependence: effects of drinking history and comorbid substance use disorder. Am J Psychiatry. 2003 Nov;160(11):2038-45. PubMed

REVIEWS AND BOOK CHAPTERS

Ciccocioppo R, Gehlert DR, Ryabinin A, Kaur S, Cippitelli A, Thorsell A, Le, AD, Hipskind, PA, Hamdouchi C, Lu J, Hembre EJ, Cramer J, Song M, McKinzie D, Morin M, Economidou D, Stopponi S, Cannella N, Braconi S, Kallupi M, de Guglielmo G, Massi M, George DT, Gilman J, Hersh, J, Tauscher JT, Hunt SP, Hommer, D, Heilig M: Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. Alcohol. 2009 Nov;43:491-8. PubMed

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