Photos of S. Majchrzak
 
Anita J. Bechtholt, Ph.D.
Title:  Program Director 
Focus areas:  Translation; neuroscience; biomarkers; technology, centers; training
Phone: (301) 443-9334
Address: 5635 Fishers Lane, Room 2046, Rockville Maryland 20892
 
Dr. Bechtholt earned her Ph.D. in Behavioral Neuroscience at Oregon Health & Science University in 2004. Her thesis work examined the role of opioid receptors in the conditioned rewarding and aversive properties of ethanol and was supported by an individual pre-doctoral National Research Service Award (NRSA) from NIAAA. Dr. Bechtholt’s postdoctoral training in the Department of Psychiatry at the University of Pennsylvania focused on understanding how antidepressants are effective, using a variety of behavioral, neurochemical, pharmacological, and genetic methods. This work was supported by a Young Investigator Award from the National Alliance for Research on Schizophrenia and Depression. Her independent research program in the Department of Psychiatry at Harvard Medical School - McLean Hospital focused on understanding the role of glial cells in the treatments and causes of psychiatric disorders including anxiety, depression, schizophrenia, and alcoholism. This work was funded by NIAAA, the National Institute of Mental Health, a Young Investigator Award from the National Alliance for Research on Schizophrenia and Depression, a grant from ABMRF/The Foundation for Alcohol Research, an Eleanor and Miles Shore Harvard Medical School Fellowship, and funds from the Shervert Frazier Research Institute.
 
Dr. Anita Bechtholt joined the NIAAA Division of Neuroscience and Behavior as a Program Director in November 2012 and transitioned to DTRR in 2014. Dr. Bechtholt administers grants related to translation, neuroscience, biomarkers, technology, centers and training.
 
Selected publications
 
Van't Veer, A., Smith, K. L., Cohen, B. M., Carlezon, W. A., Jr., & Bechtholt, A. J. (2016). Kappa-opioid receptors differentially regulate low and high levels of ethanol intake in female mice. Brain Behav, 6(9), e00523.
 
John, C. S., Sypek, E. I., Carlezon, W. A., Cohen, B. M., Ongur, D., & Bechtholt, A. J. (2015). Blockade of the GLT-1 Transporter in the Central Nucleus of the Amygdala Induces both Anxiety and Depressive-Like Symptoms. Neuropsychopharmacology, 40(7), 1700-1708. 
 
 
Ongur, D., Bechtholt, A. J., Carlezon, W. A., Jr., & Cohen, B. M. (2014). Glial abnormalities in mood disorders. Harv Rev Psychiatry, 22(6), 334-337. 
 
Smith, K. L., John, C. S., Sypek, E. I., Ongur, D., Cohen, B. M., Barry, S. M., & Bechtholt, A. J. (2014). Exploring the role of central astrocytic glutamate uptake in ethanol reward in mice. Alcohol Clin Exp Res, 38(5), 1307-1314. 
 
Van't Veer, A., Bechtholt, A. J., Onvani, S., Potter, D., Wang, Y., Liu-Chen, L. Y., . . . Carlezon, W. A., Jr. (2013). Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity. Neuropsychopharmacology, 38(8), 1585-1597.