The Collaborative Research on Addiction at NIH (CRAN) has published two Funding Opportunity Announcements (FOAs) on "Target Assessment, Engagement and Data Replicability to Improve Substance Use Disorders Treatment Outcomes (R33) and (R21/R33).  

Areas supported by this FOA include research to generate and conduct preliminary tests of targeted addiction treatment to address multiple substances, which may include alcohol, tobacco and other drug use (ATOD).

For details, please see the links below.

To view PAR-16-352 (R33):
      https://grants.nih.gov/grants/guide/pa-files/PAR-16-352.html

To view PAR-16-353 (R21/R33): 
    http://grants.nih.gov/grants/guide/pa-files/PAR-16-353.html