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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Alcohol and other substance use to cope with social anxiety
This article was first published in NIAAA Spectrum Volume 15, Issue 2. Using alcohol to cope with social anxiety is associated with increased substance use and more consequences among young adults, according to a study by National Institute on Alcohol Abuse and Alcoholism (NIAAA)-supported researchers. The findings also suggest that young adults who drink to cope with social anxiety experience...
NIAAA Guidance for Conducting Alcohol Administration Studies with Human Participants, 2023
PREAMBLE Research involving the administration of alcohol to human research participants is a critical experimental approach to address fundamental questions on the pharmacokinetics and pharmacodynamic responses to alcohol and underlying biobehavioral mechanisms, as well as the etiology, treatment, and prevention of alcohol use disorder (AUD). Furthermore, in the context of early medication development, alcohol administration studies are important to investigate...

News Release

Study Associates Alcohol Use Patterns With Body Mass Index
For Release

The body mass index (BMI) of individuals who drink alcohol may be related to how much, and how often, they drink, according to a new study by researchers at the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism (NIAAA). In an analysis of data collected from more than 37,000 people who had never smoked, researchers found that...

NIH HEAL Initiative Concept: Developing an Evidence Base for OUD-AUD Interventions
Mark Egli, Ph.D. May 09, 2023 Background At least 30% of people with OUD also have AUD. Research projects dedicated to OUD treatment and prevention do not exclude subjects who drink, but seldom explicitly recruit subjects with AUD. Reciprocal relationships between opioid use and alcohol use sometimes seen in treatment contexts such that reduced opioid misuse and opioid agonist therapy...
Medications Development Program

Treatment for alcohol use disorder (AUD) includes behavioral treatments such as mutual support groups and individual therapy, as well as pharmaceutical treatments. Often these are used in combination. Currently, there are three Food and Drug Administration (FDA)-approved medications for the treatment of AUD: Disulfiram (Antabuse®) In 1949, disulfiram became the first drug approved to treat alcoholism. The drug works by...

News Release

NIH study finds doctors miss many alcohol screening opportunities
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Physicians often fail to counsel their young adult patients about excessive alcohol use, according to a study led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. NIAAA guidelines for low risk drinking call for men to drink no more than four drinks in a day and no more than 14 drinks...

Behavioral and Drug Therapy Together Help Treat Alcoholism

A new analysis has shown that combined behavioral intervention (CBI), counseling that integrates cognitive-behavioral therapy, motivational enhancement, and techniques to enhance mutual help group participation, used alone in conjunction with naltrexone, a drug approved to help treat alcoholism, can reduce drinking in alcohol-dependent individuals. In this reanalysis of data from the COMBINE Study—the largest pharmacotherapy trial for alcoholism in the...

Levetiracetam Study
Data Access Policy, Application and Agreement NIAAA Protocol NCIG 002: A Multisite Double-Blind, Placebo-Controlled Trial of Levetiracetam Extended-Release in Very Heavy-Drinking Alcohol-Dependent Patients Description This multisite clinical trial evaluated the efficacy and safety of levetiracetam XR, for the treatment of alcohol use disorder (AUD). Study Details Sponsor: The National Institute on Alcohol Abuse and Alcoholism’s Clinical Investigations Group (NCIG) NCT #...

Announcement

New Issue of NIAAA Spectrum is Now Available!
NIAAA Spectrum is the National Institute on Alcohol Abuse and Alcoholism's (NIAAA) triannual webzine. With engaging feature articles, short news updates, and colorful graphics, NIAAA Spectrum offers accessible and relevant information on NIAAA and the alcohol research field. The latest issue is now available . In This Issue Advances in Understanding and Addressing Underage Drinking Combating underage drinking is a...
Alcohol Screening and Brief Intervention for Youth: A Practitioner's Guide
If you manage the health and well-being of 9- to 18-year-olds, this Guide is for you. “Alcohol Screening and Brief Intervention for Youth: A Practitioner’s Guide” is designed to help health care professionals quickly identify youth at risk for alcohol-related problems. NIAAA developed the Guide and Pocket Guide in collaboration with a team of underage drinking researchers and clinical specialists...

News Release

NIH findings link aldosterone with alcohol use disorder
For Release
A new study led by scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health, demonstrates that aldosterone, a hormone produced in the adrenal glands, may contribute to alcohol use disorder (AUD). The novel research, conducted in collaboration with a team of investigators in the United States and Europe, appears in the...

News Release

NIAAA honors Jonathan Gibralter with Senator Harold Hughes Award
For Release
Jonathan Gibralter, Ph.D., president of Frostburg State University (FSU), received the Senator Harold Hughes Memorial Award today from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. NIAAA Director George Koob, Ph.D., announced his selection during the 139 th meeting of the National Advisory Council on Alcohol Abuse and Alcoholism. The Hughes Award...
Early Studies on Prevention of Alcohol Use in Pregnancy

April 23-24, 1998 • Ramada Inn • Bethesda, Maryland Abstracts The Seattle Pregnancy and Health Program: A Demonstration Grant to Prevent Fetal Alcohol Syndrome and Intervene in Female Alcohol Abuse During Pregnancy Ruth E. Little, Sc.D., Ann P. Streissguth, Ph.D., and Gay M. Guzinski, M.D. From the Department of Psychiatry and Behavioral Sciences and the Department of Obstetrics and Gynecology...

Advisory Council Minutes

Minutes of the 154th Meeting of the NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM
DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM 154th Meeting of the NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM May 12, 2020 The National Advisory Council on Alcohol Abuse and Alcoholism (NIAAA) convened for its 154th meeting at 1:01 p.m. on Tuesday, May 12, 2020, via Webex videoconference and NIH...

News Release

Statement of the National Institute on Alcohol Abuse and Alcoholism on Topiramate Clinical Trial by Johnson, et al. JAMA 10/10/07
For Release

The promising results of the topiramate treatment study reported by Johnson, et al in the October 10, 2007 issue of the Journal of the American Medical Association represent another development in ongoing efforts to expand and improve treatment options for individuals with alcohol dependence (alcoholism). Topiramate significantly reduced drinking among alcohol dependent individuals. And unlike previous studies with other medications...

Preventing Alcohol, Tobacco, and Other Substance-exposed Pregnancies: A Community Affair

On September 23 and 24, 2008, the Work Group on Women, Drinking, and Pregnancy of the Interagency Coordinating Committee on Fetal Alcohol Syndrome (ICCFAS), the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the American Legacy Foundation (Legacy), a nonprofit health organization dedicated to building a world where young people reject tobacco and anyone can quit, collaborated and hosted...

Deputy Director's Page
Patricia A. Powell, Ph.D., is the Deputy Director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA). NIAAA is the largest funder of biomedical research on alcohol, with its mission being to generate and disseminate fundamental knowledge about the effects of alcohol on health and well-being and apply that knowledge to improve the diagnosis, prevention, and treatment of alcohol-related...

News Release

NIAAA Releases Physicians' Guide
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The National Institute on Alcohol Abuse and Alcoholism (NIAAA) today released The Physicians' Guide to Helping Patients with Alcohol Problems , a step by step approach to aid primary care physicians during routine office visits in identifying and advising patients at risk for or experiencing alcohol problems. Developed by NIAAA with an interdisciplinary working group of alcohol researchers and health...

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