Research supported by the National Institutes of Health (NIH) has identified brain patterns in humans that appear to underlie “resilient coping,” the healthy emotional and behavioral responses to stress that help some people handle stressful situations better than others. People encounter stressful situations and stimuli everywhere, every day, and studies have shown that long-term stress can contribute to a broad...
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
The NIAAA National Advisory Board and Extramural Advisory Board established a core of guidelines for conducting alcohol research. These guidelines include recommendations on: Clinical Trial Regulations, Policies, and Guidance – How to conduct clinical trials NIAAA Guidance for Conducting Alcohol Administration Studies with Human Participants – Considerations, requirements, and expectations for researchers engaging in alcohol administration human subject research. Guidelines...
Dr. Kenneth Kendler is a world-renowned expert on the genetics of psychiatric and substance abuse disorders. Fueled by a lifelong interest in how the human mind works, Dr. Kendler pursues research on how genes and the environment contribute to the development of alcohol use disorders, as well as other psychiatric problems. His research has transformed how we understand the relationships...
The National Institute on Alcohol Abuse and Alcoholism announces a 5-year initiative funded at approximately $50 million to define the brain circuits and mechanisms that underlie behavioral responses to chronic and excessive alcohol consumption. The multidisciplinary Integrative Neuroscience Initiative on Alcoholism ( INIA) will integrate research knowledge from animal and human studies and multiple analytic approaches to understand the behavioral...
Survey shows marijuana use disorder linked to substance use/mental disorders and disability Marijuana use disorder is common in the United States, is often associated with other substance use disorders, behavioral problems, and disability, and goes largely untreated, according to a new study conducted by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health...
Patients with a certain gene variant drank less and experienced better overall clinical outcomes than patients without the variant while taking the medication naltrexone, according to an analysis of participants in the National Institutes of Health's 2001-2004 COMBINE (Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence) Study. About 87 percent of patients with the variant who received naltrexone. experienced good...
The National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), components of the National Institutes of Health, have collaborated with HBO to create an eye-opening documentary, ADDICTION, to air on Thursday, March 15 (9:00-10:30 p.m. ET/PT). The documentary, developed with funding support from the Robert Wood Johnson Foundation, seeks to help Americans understand...
How do genes influence alcohol use disorder? Alcohol use disorder (AUD) often seems to run in families, and we may hear about scientific studies of an “alcoholism gene.” Genetics certainly influence our likelihood of developing AUD, but the story isn’t so simple. Research shows that genes are responsible for about half of the risk for AUD. Therefore, genes alone do...
Research on Promising Medications (not approved by the U.S. Food and Drug Administration [FDA]) to Treat Alcohol Use Disorder (AUD) Varenicline (Chantix®) , a medication approved for smoking cessation, was found in a recent 200-patient clinical trial conducted by NIAAA’s Clinical Investigations Group (NCIG) to reduce alcohol consumption and craving among people who are alcohol-dependent. Varenicline may work by partially...
Data Access Policy, Application and Agreement NIAAA Protocol NCIG 001: A Multisite Double-Blind, Placebo-Controlled Trial of Quetiapine Fumarate XR in Very Heavy-Drinking Alcohol-Dependent Patients Description This double-blind, randomized placebo-controlled trial evaluated the efficacy and safety of quetiapine, for the treatment of alcohol use disorder (AUD). Study Details Sponsor: The National Institute on Alcohol Abuse and Alcoholism’s Clinical Investigations Group (NCIG) ...
April 23-24, 1998 • Ramada Inn • Bethesda, Maryland Introduction The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and its co-sponsors, the Office of Research on Women’s Health and the Interagency Coordinating Committee on Fetal Alcohol Syndrome, convened a Working Group on Prevention of Risk Drinking in Pregnancy on April 23 through 24, 1998, in Bethesda, Maryland, to discuss...
A new study released today by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institutes of Health (NIH), estimates that the economic cost of alcohol and drug abuse was $246 billion in 1992, the most recent year for which sufficient data were available. This estimate represents $965 for every man...