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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIAAA Spectrum: Advancing Personalized Treatment of AUD

In a commentary published in April in the journal Alcoholism: Clinical and Experimental Research , Raye Litten, Ph.D., and other NIAAA scientists describe the evolution of our understanding of the heterogeneity of alcohol use disorder (AUD), and outline new treatment and research regimes that follow from the recognition that alcohol problems are manifested along a continuum of severity, ranging from...

News Release

[ARCHIVED] NIAAA strategic plan 2017-2021 aims to advance alcohol research across a broad spectrum of areas
For Release
Note: This document is an archived feature. View the Strategic Plan: Fiscal Years 2024-2028 at https://www.niaaa.nih.gov/about-niaaa/strategic-plan-fiscal-years-2024-… As scientific advances continue to expand our understanding of how alcohol affects human health and point to new ways to address alcohol-related harm, the National Institute on Alcohol Abuse and Alcoholism (NIAAA) has released its 2017-2021 strategic plan for research. The new plan serves...
Cross-Cutting Translational Research on the interaction of HIV and Alcohol
Title: Cross-Cutting Translational Research on the interaction of HIV and Alcohol Authors: Kendall Bryant, Ph.D., Joe Wang, Ph.D., Division of Metabolism and Health Effects Mechanism: RFA: R01, R21, R34 Purpose: The purpose of this research initiative is to encourage mechanistic studies that explore alcohol’s effects on the gut-liver-brain interactions and their pathological consequences among HIV/AIDS patients that can be translated...
Cross-Cutting Research Programs
Cross-cutting research programs are NIAAA-managed research portfolios that include topics spanning multiple research goals outlined in this strategic plan. These programs complement the Cross-Cutting Research Themes and Supporting the Mission sections of this strategic plan. Fetal Alcohol Spectrum Disorders Fetal alcohol spectrum disorders (FASD) represent the broad range of neurodevelopmental impairments and other physical effects that result from prenatal exposure...

News Release

Adult Antisocial Syndrome Common Among Substance Abusers
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Data from a recent epidemiologic survey of more than 43,000 U.S. adults show that antisocial syndromes-marked by little concern for the rights of others and violations of age-appropriate societal rules-are more common among people with substance abuse disorders than those without these disorders. The study by researchers from the National Institute on Drug Abuse (NIDA) and National Institute on Alcohol...

Collaborative Studies on Genetics of Alcoholism (COGA) Study

Scientific Mission To learn more about how our genes affect vulnerability to alcoholism, NIAAA has funded the Collaborative Studies on Genetics of Alcoholism (COGA) since 1989. Our goal is to identify the specific genes that can influence a person’s likelihood of developing alcoholism. About COGA COGA investigators have collected data on more than 2,255 extended families in which many members...

NIAAA celebrates 50 years of advancing alcohol research
This December marks the 50th anniversary of the creation of the National Institute on Alcohol Abuse and Alcoholism (NIAAA). As I look back over the past five decades, I am proud of our tremendous accomplishments and the progress we have made in alcohol research.
Appendix C Participant List

April 23-24, 1998 • Ramada Inn • Bethesda, Maryland Megan Adamson, M.D. National Institute on Alcohol Abuse and Alcoholism 6000 Executive Boulevard, Suite 402 Bethesda, Maryland 20892-7003 (301) 443-4354 (301) 443-7043 FAX E-mail: madamson@willco.niaaa.nih.gov Bruce Allen, Dr.P.H. Department of Obstetrics and Gynecology Charles R. Drew University of Medicine and Science 1621 East 120th Street Los Angeles, California 90059 (213) 563-5842...

Directors Reports

NIAAA Director's Report on Institute Activities to the 143rd Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA BUDGET LEGISLATIVE NEWS COLLABORATIVE RESEARCH ON ADDICTION AT NIH UPDATE DIRECTOR'S ACTIVITIES STAFF TRANSITIONS STAFF APPOINTMENTS HONORS & AWARDS NEW REQUESTS FOR APPLICATIONS AND PROGRAM ANNOUNCEMENTS NOTABLE NIAAA STAFF ACTIVITIES WHAT'S AHEAD NIH RESEARCH HIGHLIGHTS NIAAA COMMUNICATIONS ACTIVITIES NIAAA WELCOMES NEW COUNCIL MEMBERS NIAAA BUDGET Fiscal Year (FY) 2016 The NIAAA is currently closing out fiscal...
Guidelines for establishing and operating a Data and Safety Monitoring Board (DSMB)
Introduction This guidance is intended to assist the National Institute on Alcohol Abuse and Alcoholism (NIAAA)-supported extramural researchers in establishing and operating a Data and Safety Monitoring Board (DSMB) for clinical trials [1] funded by NIAAA. The purpose of the DSMB is to provide oversight and monitoring of the conduct of clinical trials to ensure the safety of participants and...

News Release

"Rethinking Alcohol Use Disorders: Science, Diagnosis, Treatment and Policy" -- NIAAA Track at APA Annual Meeting Press Briefing
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NIAAA ANNOUNCEMENT “Rethinking Alcohol Use Disorders: Science, Diagnosis, Treatment and Policy” NIAAA Track at APA Annual Meeting Press Briefing Arlington, Va. – The American Psychiatric Association (APA) will highlight the National Institute on Alcohol Abuse and Alcoholism (NIAAA) track “Rethinking Alcohol Use Disorders: Science, Diagnosis, Treatment and Policy” at the 159 th Annual Meeting in Toronto, Ontario, at a press...

Announcement

Dr. Gyongyi Szabo Delivers 9th Annual Jack Mendelson Honorary Lecture at the National Institutes of Health
What: The National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health, announces that Gyongyi Szabo, M.D., Ph.D. will deliver the 9th Annual Jack Mendelson Honorary Lecture. The title of her presentation is “ Mechanisms of Alcohol-Induced Organ Inflammation and Therapeutic Targets in Alcoholic Hepatitis .” Who: Gyongyi Szabo, M.D., Ph.D., is the Worcester Foundation...

News Release

Combined prenatal smoking and drinking greatly increases SIDS risk
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Children born to mothers who both drank and smoked beyond the first trimester of pregnancy have a 12-fold increased risk for Sudden Infant Death Syndrome (SIDS) compared to those unexposed or only exposed in the first trimester of pregnancy, according to a new study supported by the National Institutes of Health. SIDS is the sudden, unexplained, death of an infant...

Minority Health and Health Disparities (MHHD) and Diversity Training Resources
Commitment to Improving Research The National Institute on Alcohol Abuse and Alcoholism is committed to improving the quality and quantity of alcohol research studying underrepresented populations. Groups shown to suffer health disparities, or differences in the incidence, morbidity, or mortality associated with alcohol misuse as well as different medical, interpersonal and social consequences include: Racial and ethnic minorities Rural and...

News Release

10 percent of US adults have drug use disorder at some point in their lives
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75 percent report not receiving any form of treatment A survey of American adults revealed that drug use disorder is common, co-occurs with a range of mental health disorders and often goes untreated. The study, funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health, found that about 4 percent of Americans...

Announcement

ABCD study completes enrollment, announces opportunities for scientific engagement

The National Institutes of Health announced today that enrollment for the Adolescent Brain Cognitive Development (ABCD) Study is now complete and, in early 2019, scientists will have access to baseline data from all ABCD Study participants. There are 11,874 youth, ages 9-10, participating in the study, including 2,100 young people who are twins or triplets. All will be followed through...

ICCFASD Justice Issues Work Group
The Justice Issues Work Group – one of four work groups established by the Interagency Coordinating Committee on Fetal Alcohol Spectrum Disorders (ICCFASD) to address special issues and to plan and implement directed activities – is led by Scott Pestridge, Senior Policy Advisor, Office of Juvenile Justice and Delinquency Prevention. Mr. Pestridge is also the U.S. Department of Justice representative...

News Release

Heart medication shows potential as treatment for alcohol use disorder
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A medication for heart problems and high blood pressure may also be effective for treating alcohol use disorder, according to a new study by researchers at the National Institutes of Health and their colleagues. The study presents converging evidence from experiments in mice and rats, as well as a cohort study in humans, suggesting that the medication, spironolactone, may play...
Collaborative Study on the Genetics of Alcoholism (COGA)
Elizabeth Powell, Ph.D. February 08, 2024 Purpose The purpose of the Collaborative Study on the Genetics of Alcoholism (COGA) is to advance knowledge about the complex influences of gene and environment on development and progression of alcohol use disorder (AUD). From its inception, COGA has generated and utilized extensive arrays of genotypic and phenotypic data from families densely affected by...

News Release

Mouse Model Links Alcohol Intake to Marijuana-Like Brain Compounds: New Pathway Presents Target for Medication Development
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Brain molecules similar to the active compound in marijuana help to regulate alcohol consumption, according to new reports by scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), Bethesda, Maryland, and a separate NIAAA-supported group at several New York state research institutions. In studies conducted with a strain of mice known to have a high preference for alcohol...

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