The following information is for Administrative Supplement Applications to be submitted electronically in response to the NIH Funding Opportunity Announcement (FOA) Number PA-14-077, Administrative Supplement to Existing NIH Grants and Cooperative Agreements (Parent Admin Supplement FOA),  published on January 30, 2014 in the NIH Guide to Grants and Contracts:

Prior approval from NIAAA is required before submission of an Administrative Supplement/Extension Application. As soon as it is apparent that a grant may need additional funds, NIAAA recommends that the Principal Investigator (PI) contact the Program Official (PO) named on the parent grant to discuss the possible funding options available. If the PO deems that an Administrative Supplement may be considered, permission to electronically submit an Administrative Supplement Application must be made to the NIAAA PO in writing by the  grant recipient’s Authorized Organizational Representative (AOR) at least 6 weeks before the submission of the application.  The NIAAA Office of Extramural Activities will send a written notification to the applicant grantee approving submission of the Administrative Supplement Application.  Note that granting of permission to submit an Administrative Supplement Application is not an assurance of funding

NIAAA awards well-justified Administrative Supplements only when necessary to the successful conduct of a funded project and only if funds are available. Increased funding above study section-recommended levels or outside the fiscal year funding policies generally is for items resulting from events unanticipated when the parent application originally was submitted and must not represent changes in the basic goals or intent of the project. 

Administrative Supplement Requests must be within the IRG-Council-approved scope and must not deviate from the scope of the funded parent grant.

Administrative Supplements to support a new specific aim may not be accepted. In this instance, the applicants are encouraged to submit a Revision Application (Competitive Supplement), which are peer-reviewed.

NIAAA may fund Administrative Supplements (Type 3)  to cover unanticipated costs of a project and may include the following examples:

  • Preservation of a unique research material or resource that may otherwise be lost, such as maintaining a unique knockout mouse model.
  • Addition of patients, populations, or other items related to a protocol due to enrollment issues, a need for statistically significant data, or responses to protocol and Data and Safety Monitoring Board (DSMB) reviews.
  • Provision for an orderly termination or temporary continuation of support to prevent loss of research resources or hardship of personnel, which includes taking advantage of a rare event with an immediate need, such as salvaging a rare animal model.
  • Replacement of equipment, supplies, and time lost due to a natural disaster or loss of equipment originally available to the project from other sources.
  • Increased cost of equipment and related services, e.g., data analysis, animal purchase and care costs.

NIAAA may not consider supporting Administrative Supplements that will pay for a PI to move in a new scientific direction; obtain preliminary data for another contemplated research effort; use a new technology or an animal model not specified in the application; accomplish new specific aims that are not part of the original IRG-Council approved grant applications; moving expenses associated with the PI’s transfer from one institution to another. If additional funds are needed for such purposes, investigators should apply for another grant.

NIAAA may support Administrative Supplements made for the purpose of extending the period of support to assure orderly termination of a project or to support a project for a limited time pending a decision or action to continue or discontinue support (for example, when there is an IRG or Council deferral and support would terminate before completion of review).  Extensions of projects made for this purpose should be for periods as brief as possible, but in no case should they exceed 1 year. 

NIAAA may fund Administrative Extension (Type 3)  of investigator-initiated clinical trial grants or cooperative agreements that may not be completed on time due to the following:

  • Difficulties in obtaining suitable study subject and/or agent
  • Difficulties meeting enrollment schedule
  • Difficulties obtaining assurances and certifications
  • Difficulties with access to suitable facilities
  • External hold ups at regulatory of funding agencies (not related to safety)
  • Litigation involving any of the above
  • Changes in public health policy or standards of care


Administrative Supplements and Extensions are reviewed by Program Staff for scientific merit. Administrative Supplement Requests that exceed $100,000 or 25% (whichever is higher) of direct cost of the active year of the parent grant, will be reviewed by the National Advisory Council on Alcohol Abuse and Alcoholism.

THE PARENT GRANT MUST BE ACTIVE FOR AT LEAST ANOTHER 12 MONTHS AT THE TIME OF SUBMISSION. Exceptions may be granted after discussion with the Program Officer, Chief of the Grants Management Branch, and Director of the Office of Extramural Activities.

Non-compliant Administrative Supplement Applications may be rejected.

Ms. Judy Fox
Chief, Grants Management Branch
Office of Extramural Activities, NIAAA


Dr. Abraham Bautista
Director, Office of Extramural Activities