National Institute on Alcohol Abuse and Alcoholism (NIAAA)
The goal of the Section on Neural Circuits is to understand how genetic and environmental insults affect the computation of neural signals within brain networks to cause neurodevelopmental disorders like autism, epilepsy and attention-deficit/hyperactivity disorder.
Mechanisms for mitochondrial dysfunction and apoptosis in alcoholic and nonalcoholic fatty liver and tissue injury – Dr. Song and his lab members have studied regulations and roles of the two enzymes involved in metabolism of alcohol and acetaldehyde: the ethanol-inducible cytochrome P450 2E1 (CYP2E1) and mitochondrial aldehyde dehydrogenase (ALDH2). In particular, the functional implications of increased CYP2E1 and decreased ALDH2...
The goal of the Laboratory of Biophotonics and Quantum Biology (LBQB) is to develop advanced imaging and spectroscopy techniques for studying protein-protein interaction under physiological conditions and for developing second-generation biosensors. We are particularly interested in developing new tools and approaches using fluorescent proteins for studying proteins that modulate synaptic behavior. Techniques used in LBQB include two-photon laser scanning confocal...