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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NPY Suppresses Stress-Induced Alcohol Relapse in Rats

Neuropeptide Y (NPY) is a naturally-occurring brain molecule that helps regulate emotional behavior, stress responses, and other functions. Much research evidence suggests that NPY also plays an important role in regulating alcohol consumption. Scientists led by NIAAA Clinical Director Markus Heilig, M.D., Ph.D., recently investigated the effect of NPY on stress-induced relapse to alcohol use. Relapse prevention is an important...

Molecule hijacks enzyme to boost alcohol metabolism
An experimental compound empowers an enzyme to help process acetaldehyde, a toxic metabolite of alcohol, according to new research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The findings, now online in the Proceedings of the National Academy of Sciences (PNAS), might lead to new treatments to help people with impaired ability to metabolize acetaldehyde and other...
Twitter Chat: Understanding Alcohol and Your Health
April is Alcohol Awareness Month – a good time to learn more about how alcohol use impacts your health and examine your own drinking habits. Bring your health-related questions and come chat with an NIAAA expert. Date: Tuesday, April 28, at 1 p.m. ET. Hashtag: #NIAAAchat
Study supports single-question alcohol screen for adolescents
Findings also endorse use of NIAAA youth screening guide A single screening question about drinking frequency in the past year could help doctors identify adolescents at risk for alcohol problems, according to a new study funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. Conducted by researchers at the University of...
Receptor Variant Influences Dopamine Response to Alcohol

A genetic variant of a receptor in the brain’s reward circuitry plays an important role in determining whether the neurotransmitter dopamine is released in the brain following alcohol intake, according to a study led by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. Dopamine is involved in transmitting the euphoria...

Diet Quality Worsens as Alcohol Intake Increases

People who drink more are also likely to eat less fruit and consume more calories from a combination of alcoholic beverages and foods high in unhealthy fats and added sugars, according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Cancer Institute (NCI), and the U.S. Department of Agriculture (USDA). The study...

Scientists Identify Gene That Influences Alcohol Consumption

A variant of a gene involved in communication among brain cells has a direct influence on alcohol consumption in mice, according to a new study by scientists supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), and the U.S. Army. Scientists do not know yet whether a similar gene variant...

Study Links Receptor to Stress-Induced Alcohol Relapse

Relapse to uncontrolled drinking after periods of sobriety is a defining characteristic of alcoholism and is often triggered by stress. A new study in rats reports that a specific receptor for a stress-response transmitter may play an important role in stress-induced relapse. The study, a collaboration between scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of...

New issue of Alcohol Research: Current Reviews

This issue of ARCR, Alcohol and the Immune System,reviews a broad range of immune-relevant alcohol research, detailing how alcohol-induced disruption of immune pathways can impair the body’s ability to defend against infection, contribute to organ damage associated with alcohol consumption, impede recovery from tissue injury, and potentially contribute to alcohol use disorder among other issues. You can access the full...

Adolescent Alcohol Activates Hippocampal Astrocytes in Adulthood
NIAAA-supported researchers at the Duke University and Durham Veterans Affairs Medical Centers continue to refine our understanding of how repeated exposure to alcohol during adolescence causes long-lasting structural and functional abnormalities in the brain. Earlier this year, Duke scientists led by Dr. Mary-Louise Risher looked at how alcohol affects the hippocampus, a region of the brain associated with memory and...
Links between alcohol use and suicidal behavior

The latest article from Alcohol Research Current Reviews explores links between alcohol use and suicidal behavior. Research on associations of suicidal behavior, including suicide and suicide attempt, with alcohol use disorder (AUD) and acute use of alcohol (AUA) are discussed, with an emphasis on data from meta-analyses. Based on psychological autopsy investigations, results indicate that AUD is prevalent among individuals...

National Drug and Alcohol Facts Week® 2020
The National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) announced the 10th annual National Drug and Alcohol Facts Week® (NDAFW), will take place March 30 through April 5, 2020. NDAFW is a week of educational events that annually brings together teens and scientific experts to SHATTER THE MYTHS® about substance use and...

Canceled: National Drugs and Alcohol Chat Day
Based on guidance by NIH regarding COVID-19, the CHAT DAY scheduled for Wednesday, April 1, 2020 has been cancelled. Please stay tuned - we will connect with all registrants about the next chat day opportunity. You can still access the 2019 transcript to see if your questions were answered.
Preventing Alcohol, Tobacco, and Other Substance-exposed Pregnancies: A Community Affair

On September 23 and 24, 2008, the Work Group on Women, Drinking, and Pregnancy of the Interagency Coordinating Committee on Fetal Alcohol Syndrome (ICCFAS), the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the American Legacy Foundation (Legacy), a nonprofit health organization dedicated to building a world where young people reject tobacco and anyone can quit, collaborated and hosted...

Alcohol Research Awards (Clinical Trial Not Allowed, R24)

Kathy Jung, Ph.D., Mark Egli, Ph.D., Gary Murray, Ph.D. Reissuance of PAR 17 170 Alcohol Research Resource Awards (R24, Clinical Trial Not Allowed) Purpose The purpose of the Resource-Related Research Projects (R24, clinical trial not allowed) grant mechanism is to support investigator-initiated research resource projects that will provide resources to other investigators who conduct biomedical research appropriate to the mission...

Alcohol Consumption During the Pandemic: Extending Longitudinal Survey and Analysis
Gregory Bloss, M.A., M.P.P./ Program Director, Division of Epidemiology and Prevention Research Acquisition Type/Actions The National Institute on Alcohol Abuse and Alcoholism (NIAAA) requests approval from the NIAAA Advisory Council to allow Research Triangle Institute (RTI) International to submit a contract proposal in response to a sole-source request for proposal. This acquisition, for other than full and open competition, is...
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