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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Semaglutide shows promise as a potential alcohol use disorder medication
This article was first published in NIAAA Spectrum Volume 16, Issue 1. Intramural scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA), and collaborators from The Scripps Research Institute, found that semaglutide reduces alcohol consumption and binge-like drinking in a rodent model of alcohol misuse. Published in the June 2023...
Make Referrals: Connect Patients to Alcohol Treatment That Meets Their Needs
For some patients, alcohol treatment referral may not be a single event but instead part of an ongoing process of engagement. You can help patients surmount barriers to following through on a treatment referral by countering the effects of stigma, conveying that treatment can be effective, and offering a range of choices for care.
Alcohol Research Resource (R24 and R28) Awards
NIAAA’s Alcohol Research Resource (R24 and R28) Awards support investigator-initiated projects that develop resources to serve the broader alcohol-research community. Resources include biological specimens, animals, data, materials, tools, or services made available to any qualified investigator to accelerate alcohol-related research in a cost-effective manner. Please send inquiries to the Principal Investigator listed below or contact the appropriate NIAAA Program Director...
Definición de niveles y patrones de consumo de alcohol
Consumo moderado Según las Guías alimentarias para estadounidenses, 2020-2025, los adultos en edad legal de beber pueden elegir no beber alcohol o, cuando beben, limitar el consumo a dos bebidas o menos en un día para los hombres y a una bebida o menos en un día para las mujeres. Beber menos es mejor para la salud que beber más...
Alcohol Use in the United States: Age Groups and Demographic Characteristics
Prevalence of Lifetime Drinking People Ages 12 and Older According to the 2023 National Survey on Drug Use and Health (NSDUH), 224.3 million people ages 12 and older (79.1% in this age group) reported that they drank alcohol at some point in their lifetime. 1,2 This includes: 111.1 million males ages 12 and older (80.1% in this age group) 1,2...
Sober-curious young Americans may be changing the conversation around alcohol
This article was first published in NIAAA Spectrum Volume 16, Issue 3 . According to data from the 2023 National Survey on Drug Use and Health, 68% of adults ages 21 and older in the United States drink alcohol. 1 At the same time, researchers believe that the recent “sober-curious” movement may be encouraging some people to reevaluate their relationship...
Anti-smoking medication shows promise for treating alcohol dependence

NIH researchers seek to expand treatment options A smoking-cessation medication may be a viable option for the treatment of alcohol dependence, according to a study by scientists at the National Institutes of Health. The study found that varenicline (marketed under the name Chantix), approved in 2006 to help people stop smoking, significantly reduced alcohol consumption and craving among people who...

Brain Pathways to Recovery from Alcohol Dependence (Agenda)

November 8, 2013, 8:30am – 5:30 pm Room 24, San Diego Convention Center 8:30 am - Welcome / Opening Remarks Kenneth Warren, Ph.D. Acting Director, National Institute on Alcohol Abuse and Alcoholism Antonio Noronha, Ph.D., Director, Division of Neuroscience and Behavior, NIAAA 8:40 am - Overview on brain pathways to recovery from alcohol dependence Changhai Cui, Ph.D., Program Director, Division...

Alcohol Researchers Identify a Genetic Basis of Pain Response

A common genetic variant influences individual responses and adaptation to pain and other stressful stimuli and may underlie vulnerability to many psychiatric and other complex diseases, reports David Goldman, M.D., Chief, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, and colleagues at NIAAA and the University of Michigan. COMT val 158met Genotype Affects m-Opioid Neurotransmitter Responses to a...

NIAAA Seeks Knowledge of Alcohol and HIV/AIDS Interactions

The National Institute on Alcohol Abuse and Alcoholism today announces a 5-year prospective study on the role of alcohol use and abuse in determining patient outcomes for aging veterans with and without HIV infection. The study is an expansion of the ongoing Veterans Aging Cohort Study (VACS), initiated in 1999 and supported by a number of NIH components including the...

Gene Therapy Technique Reduces Alcohol Consumption in Rats

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory report in the current Journal of Neurochemistry (Volume 78, Number 5) that they used gene therapy techniques to increase levels of dopamine D2 (DRD2) receptors and reduce drinking in rats previously trained to self-administer alcohol. Panayotis Thanos, Ph.D., Nora Volkow, Ph.D., and colleagues used a partially inactivated virus as a...

Alcohol Researchers Localize Brain Region That Anticipates Reward

Researchers at the National Institute on Alcohol Abuse and Alcoholism have found that anticipation of increasing monetary rewards selectively activates the human nucleus accumbens of the ventral striatum. Since this brain region is implicated in animal studies of alcohol and drug self-administration, the research may help lead to methods for understanding the biological basis of alcohol and drug craving in...

Alcohol Researchers Prove Success with Primary Care Interventions

Michael Fleming, M.D., M.P.H., and colleagues at the University of Wisconsin Medical School in Madison report in the April 2 Journal of the American Medical Association results from Project TrEAT (Trial for Early Alcohol Treatment), the first large U.S. clinical trial to test the effectiveness of brief physician advice for intervening with nondependent problem drinkers. Supported by a grant from...

NIAAA/VA Researchers Identify Possible Site of Alcohol Damage

Alcohol Damage Bethesda, Maryland. Researchers at Harvard Medical School and the Brockton/West Roxbury Veterans Administration Medical Center report in today's issue of The Journal of Cell Biology a molecular action of alcohol that may produce some of the damage seen in fetal alcohol syndrome (FAS) and fetal alcohol effects (FAE). The same mechanism may play a role in such adult...

Heavy Alcohol Consumption During Adolescence Compromises Hippocampal Development

Binge drinking is common during adolescence, a period of rapid brain development. In this study, researchers used adolescent nonhuman primates to examine the effects of long-term binge alcohol consumption on brain development. They found that an 11-month period of heavy binge alcohol consumption by nonhuman primates led to a significant and persistent reduction in neurogenesis – the birth and maturation...

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