National Institute on Alcohol Abuse and Alcoholism (NIAAA)

People who drink more are also likely to eat less fruit and consume more calories from a combination of alcoholic beverages and foods high in unhealthy fats and added sugars, according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Cancer Institute (NCI), and the U.S. Department of Agriculture (USDA). The study...

An experimental compound repaired a defective alcohol metabolism enzyme that affects an estimated 1 billion people worldwide, according to research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The findings, published Jan. 10, 2010 in the advance online edition of Nature Structural and Molecular Biology, suggest the possibility of a treatment to reduce the health problems associated...

Alcohol-related deaths among U.S. college students rose from 1,440 deaths in 1998 to 1,825 in 2005, along with increases in heavy drinking and drunk driving, according to an article in the July supplement of the Journal of Studies on Alcohol and Drugs. The special issue describes the results of a broad array of research-based programs to reduce and prevent alcohol-related...

A family-based prevention program designed to help adolescents avoid substance use and other risky behavior proved especially effective for a group of young teens with a genetic risk factor contributing toward such behavior, according to a new study by researchers at the University of Georgia. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug...

Many people of East Asian descent possess an enzyme deficiency that causes their skin to redden, or flush, when they drink alcohol. Scientists from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and Japan's KurihamaAlcoholCenter now caution that heavy alcohol consumption greatly increases the risk for esophageal cancer among such individuals, who comprise about 8 percent of the world's...

A new Web site and booklet from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) could help many people reduce their risk for alcohol problems. Called Rethinking Drinking, the new materials present evidence-based information about risky drinking patterns, the alcohol content of drinks, and the signs of an alcohol problem, along with information about medications and other resources to...

Bethesda, Maryland — Ting-Kai Li, M.D., director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) since November 2002, announced today that he will step down from his post and retire from Federal service, effective October 31, 2008. Kenneth R. Warren, Ph.D., the NIAAA Deputy Director since February 2008, will serve as Acting Director of the Institute while a...

In recent years, a class of small molecules known as microRNAs have been found to play an important role in regulating gene products in most animal and plant species. A new study now indicates that microRNA may influence the development of alcohol tolerance, a hallmark of alcohol abuse and dependence. Researchers supported by the National Institute on Alcohol Abuse and...

National Institute on Alcohol Abuse and Alcoholism (NIAAA) Director Ting-Kai Li, M.D. recently appointed Kenneth R. Warren, Ph.D., as NIAAA deputy director. “Dr. Warren has filled many leadership roles throughout his long and distinguished career at NIAAA” said Dr. Li. “His extensive experience in research and administration will serve the institute well.” Dr. Warren joined NIAAA in 1976 as a...

In a special supplement to Pediatrics, edited and sponsored by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), physicians will have access in one place to the reviews and analyses of current research on biological, behavioral, and environmental changes during childhood and adolescence that foster the initiation, maintenance, and acceleration of illegal use of alcohol by underage youth. This...

A new, interactive video training program from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), demonstrates quick and effective strategies for screening patients for heavy drinking and helping them to cut down or quit. “The video scenarios demonstrate evidence-based techniques for assessing and managing at-risk drinking and alcohol use disorders,” says...

Changes to genetic material in the brain may help induce the anxiety that is characteristic of alcohol withdrawal, according to a new study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). The finding points to possible therapies to prevent withdrawal-related anxiety, a driving force behind alcohol use among dependent...

Inherited variations in the amount of an innate anxiety-reducing molecule help explain why some people can withstand stress better than others, according to a new study led by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). “Stress response is an important variable in vulnerability to alcohol dependence and other...

How much and how often people drink – not just the average amount of alcohol they consume over time – independently influence the risk of death from several causes, according to a new study by researchers at the National Institutes of Health (NIH). "Taken together, our results reinforce the importance of drinking in moderation. In drinkers who are not alcohol...

A brain circuit that underlies feelings of stress and anxiety shows promise as a new therapeutic target for alcoholism, according to new studies by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). In preclinical and clinical studies currently reported online in Science Express, NIAAA Clinical Director Markus Heilig, M.D...

Patients with a certain gene variant drank less and experienced better overall clinical outcomes than patients without the variant while taking the medication naltrexone, according to an analysis of participants in the National Institutes of Health's 2001-2004 COMBINE (Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence) Study. About 87 percent of patients with the variant who received naltrexone. experienced good...

Asking emergency department patients about their alcohol use and talking with them about how to reduce harmful drinking patterns is an effective way to lower rates of risky drinking in these patients, according to a nationwide collaborative study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the Substance Abuse and Mental Health Services Administration (SAMHSA). Emergency...

A variant of a gene involved in communication among brain cells has a direct influence on alcohol consumption in mice, according to a new study by scientists supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), and the U.S. Army. Scientists do not know yet whether a similar gene variant...

The promising results of the topiramate treatment study reported by Johnson, et al in the October 10, 2007 issue of the Journal of the American Medical Association represent another development in ongoing efforts to expand and improve treatment options for individuals with alcohol dependence (alcoholism). Topiramate significantly reduced drinking among alcohol dependent individuals. And unlike previous studies with other medications...

Two Institutes at the National Institutes of Health (NIH) have been honored with the prestigious Governors Award by the Academy of Television Arts and Sciences for their work with HBO on the Addiction Project. "Addiction" is a 14-part documentary television series and multimedia initiative revealing the science of addiction, its treatment, recovery, and its costs to families and society. A...