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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

HIV/AIDS and Alcohol Research Program
Welcome to the Alcohol and HIV/AIDS Research Program HIV/AIDS AND ALCOHOL RESEARCH AREAS RESEARCH PRIORITIES FUNDED RESEARCH RESOURCES CONTACT HIV/AIDS and Alcohol Extraordinary progress in HIV/AIDS research has led to the development of interventions and medications to reduce transmission and has transformed an almost inevitably fatal disease into a preventable and treatable disorder. People with HIV/AIDS can achieve their full...

News Release

Faye Calhoun Named NIAAA Deputy Director
For Release

Dr. Faye Calhoun was recently named deputy director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), a component of the National Institutes of Health (NIH). "Dr. Calhoun brings extensive experience and expertise to her new position," says NIAAA Director Ting-Kai Li, M.D. "I am confident her imaginative and creative leadership will help the Institute address future challenges in...

Epi-Genetic Modulators of Fear Extinction in Alcohol Dependence
VOLUNTEERS NEEDED Doctors at the National Institutes of Health (NIH) seek healthy volunteers 21-65 years of age to participate in a study researching if alcohol dependence and early life stress affect the ability to learn to feel calm. All study-related tests and procedures are provided at no cost to you. Compensation may be provided. Study highlights include: 2 day, 1...

News Release

NIH-led study identifies genetic variant that can lead to severe impulsivity
For Release

A multinational research team led by scientists at the National Institutes of Health has found that a genetic variant of a brain receptor molecule may contribute to violently impulsive behavior when people who carry it are under the influence of alcohol. A report of the findings, which include human genetic analyses and gene knockout studies in animals, appears in the...

Announcement

In Memoriam: Dr. Ting-Kai Li, former NIAAA Director
With deep sadness, the National Institute on Alcohol Abuse and Alcoholism (NIAAA) community mourns the passing of Ting-Kai Li, M.D., a renowned scientist who served as the Institute's director from 2002 to 2008. Dr. Li died on November 18, 2018, at Duke University Hospital in Durham, North Carolina. Dr. Li’s contributions to the alcohol field were monumental. He was a...

Advisory Council Minutes

National Advisory Council Meeting - February 16-17, 2011
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The National Advisory Council on Alcohol Abuse and Alcoholism (NIAAA) convened for its 126th meeting at 5:30 p.m. on February 16, 2011, at the Fishers Lane Conference Center in Rockville, Maryland, in closed session for a review of grant applications and a Merit Award extension. The meeting recessed at 7:00 p.m. The Council reconvened on February 17, 2011, at 8:00...

LMP - Section on Transmitter Signaling (TS)

Mission Statement: Focuses on identifying the molecular components of intracellular signaling cascades. Ion Channel Modulation by Second Messenger Systems The Section on Transmitter Signaling focuses primarily on determining the molecular mechanisms underlying G-protein coupled receptor (GPCR) modulation of voltage-gated Ca2+ channels in neuronal systems using electrophysiological, optical, molecular, and biochemical techniques. A consequence of modulation, which usually manifests as a...

A Wearable Alcohol Biosensor
Kathy Jung, Division of Metabolism and Health Effects Purpose The purpose of this announcement is to renew the National Institute on Alcohol Abuse and Alcoholism’s initiative on the development of a wearable alcohol biosensor. Currently, assessment of alcohol consumption relies primarily on inherently subjective self-report through surveys ranging from AUDIT, AUDIT -C, to Timeline Follow Back and other more extensive...
15-AA-0127 - Epi-Genetic Modulators of Fear Extinction in Alcohol Dependence
DO YOU DRINK ALCOHOL TO DEAL WITH STRESS? Doctors at the National Institutes of Health (NIH) seek volunteers between 21-65 year of age who drink heavily and/or had a stressful childhood to participate in a study looking at the effect of alcohol abuse and early life stress on the ability to feel calm. All study-related tests and procedures are provided...

News Release

Receptor Variant Influences Dopamine Response to Alcohol
For Release

A genetic variant of a receptor in the brain’s reward circuitry plays an important role in determining whether the neurotransmitter dopamine is released in the brain following alcohol intake, according to a study led by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. Dopamine is involved in transmitting the euphoria...

News Release

Youth Drinking Trends Stabilize, Consumption Remains High
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Although the prevalence of underage drinking has decreased since its peak in the late 1970s, drinking by youth has stabilized over the past decade at disturbingly high levels. The findings, part of a new analysis of youth drinking trends by researchers at the National Institutes of Health (NIH), appear in the September, 2004 issue of Alcoholism: Clinical and Experimental Research...

News Release

Sex hormone-sensitive gene complex linked to premenstrual mood disorder
For Release
Dysregulated cellular response to estrogen and progesterone suspected. National Institutes of Health (NIH) researchers have discovered molecular mechanisms that may underlie a woman’s susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period. Such premenstrual dysphoric disorder (PMDD) affects 2 to 5 percent of women of reproductive age, whereas less severe premenstrual syndrome (PMS)...

News Release

NIAAA Names 2002 Senator Harold Hughes Memorial Award Winner
For Release

Barbara Foley, R.N., Executive Director and Co-Founder of Emergency Nurses CARE (EN CARE) of Alexandria, Virginia, today was named the fourth recipient of the National Institute on Alcohol Abuse and Alcoholism’s annual Senator Harold Hughes Memorial Award. The award is made annually to a nonresearcher who has used alcohol research findings to foster research, prevention, or treatment, thereby translating research...

Agenda on Working Group on Prevention of Risk Drinking in Pregnancy

April 23-24, 1998 • Ramada Inn • Bethesda, Maryland Agenda Working Group on Prevention of Risk Drinking in Pregnancy Thursday, April 23, 1998 - Embassy II & III Time Session 8:00 a.m. Registration - Continental Breakfast 8:30 a.m. Welcome and Charge to the Working Group Chair: Mary Dufour, M.D., M.P.H., Deputy Director, NIAAA Enoch Gordis, M.D., Director, NIAAA Joyce Rudick...

Directors Reports

NIAAA Director's Report on Institute Activities to the 156th Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Virtual Meeting Table of Contents IN MEMORIAM NIAAA BUDGET NIAAA DIRECTOR'S ACTIVITIES STAFF TRANSITIONS RECENTLY ISSUED FUNDING OPPORTUNITYANNOUNCEMENTS NOTABLE NIAAA STAFF ACTIVITIES WHAT'S AHEAD? NI RESEARCH HIGHLIGHTS NIAAA COMMUNICATIONS AND PUBLIC LIAISON ACTIVITIES IN MEMORIAM Kathleen (Kathy) Carroll, Ph.D. , passed away in December 2020. Dr. Carroll was a clinical scientist in the Yale Department of Psychiatry who made seminal...
Alcohol and Pregnancy in the United States
According to the Behavioral Risk Factor Surveillance Survey (BRFSS)—a survey of more than 400,000 people by the U.S. Centers for Disease Control and Prevention—during 2018–2020, nearly 14% of pregnant people ages 18 to 49 reported current drinking. 1 Also according to BRFSS, during 2018–2020, about 5% of pregnant people ages 18 to 49 reported binge drinking in the past 30...

News Release

Gene Variant Increases Risk for Alcoholism Following Childhood Abuse
For Release

Girls who suffered childhood sexual abuse are more likely to develop alcoholism later in life if they possess a particular variant of a gene involved in the body’s response to stress, according to a new study led by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). The new finding...

Sleep Dysfunction as a Core Feature and Intervention Target in Alcohol-induced Hyperkatifeia
Shailesh Kumar September 07, 2023 Purpose The concept aims to explore the influence of sleep disturbance on hyperkatifeia during alcohol withdrawal. It seeks to gain a comprehensive understanding of hyperkatifeia’s features and its connection with sleep disruptions, while also developing focused interventions to alleviate symptoms, enhance emotional regulation, and improve the well-being of individuals experiencing hyperkatifeia. Background Alcohol induced withdrawal...
NIAAA Guidance for Conducting Alcohol Administration Studies with Human Participants, 2023
PREAMBLE Research involving the administration of alcohol to human research participants is a critical experimental approach to address fundamental questions on the pharmacokinetics and pharmacodynamic responses to alcohol and underlying biobehavioral mechanisms, as well as the etiology, treatment, and prevention of alcohol use disorder (AUD). Furthermore, in the context of early medication development, alcohol administration studies are important to investigate...

News Release

Stress Hormone Linked to Increased Alcohol Consumption in Animal Model
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Researchers at the National Institute on Alcohol Abuse and Alcoholism and the National Institute of Child Health and Human Development report in the current issue of Alcoholism: Clinical and Experimental Research (Volume 24, Number 5) results from the first study to determine whether future drinking may be predicted by response to stress during infancy. Monkeys that responded with high cortisol...

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