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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Researchers Link PKA to Voluntary Alcohol Consumption and Alcohol Effects

Researchers at the University of Washington report in the May 15 Journal of Neuroscience (Volume 20, RC75) the first direct evidence in mice that protein kinase A (PKA) signaling regulates both alcohol-seeking behavior and sensitivity to some of the effects of alcohol intoxication. Given a choice between plain water and solutions containing alcohol, mice missing the RIIB subunit of PKA...

NIAAA SfN Satellite Event
Satellite Symposium to Society for Neuroscience 2014 Annual Meeting PTSD, the Amygdala, and Alcohol Use Disorders November 14, 2014, 9:00 am - 6:00 pm Washington, DC Convention Center Room 207B Agenda 9:00 AM - Welcome 9:05 AM - Introduction: PTSD, the Amygdala, and the Connection to Alcohol Abuse George Koob, Ph.D., Director, National Institute on Alcohol Abuse and Alcoholism Session...
Using social media to better understand, prevent, and treat substance use

NIH announces 11 awards funded across three Institutes More than $11 million over three years will be used to support research exploring the use of social media to advance the scientific understanding, prevention, and treatment of substance use and addiction. The awards are funded through the Collaborative Research on Addiction at NIH (CRAN), an NIH consortium involving the National Institute...

Diet Quality Worsens as Alcohol Intake Increases

People who drink more are also likely to eat less fruit and consume more calories from a combination of alcoholic beverages and foods high in unhealthy fats and added sugars, according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Cancer Institute (NCI), and the U.S. Department of Agriculture (USDA). The study...

Molecule Repairs Alcohol Metabolism Enzyme

An experimental compound repaired a defective alcohol metabolism enzyme that affects an estimated 1 billion people worldwide, according to research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The findings, published Jan. 10, 2010 in the advance online edition of Nature Structural and Molecular Biology, suggest the possibility of a treatment to reduce the health problems associated...

Finding May Explain Link Between Alcohol and Certain Cancers

Drinking alcoholic beverages has been linked to an increased risk of upper gastrointestinal cancer and other types of cancer. Researchers looking for the potential biochemical basis for this link have focused on acetaldehyde, a suspected carcinogen formed as the body metabolizes alcohol. In the journal Nucleic Acids Research (vol. 33, num. 11), scientists from the National Institute on Alcohol Abuse...

Scientists Propose Neuroscience Framework for Diagnosing Addictions

Scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health, propose using an assessment tool to diagnose addictive disorders that considers addiction-related behaviors, brain imaging, and genetic data. According to a new review article, the Addictions Neuroclinical Assessment (ANA) would facilitate future understanding of the origin of addiction at a biological level...

National Advisory Council Meeting - February 6-7, 2008

NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM Summary of the 117th Meeting February 6-7, 2008 The National Advisory Council on Alcohol Abuse and Alcoholism convened for its 117th meeting at 5:30 p.m. on February 6, 2008, at the FishersLaneConferenceCenter in Rockville, Maryland, in a closed session, and again at 8:15 a.m. on February 7, also in closed session. The...

NIH study finds missed opportunities for underage alcohol screening

Physicians often fail to ask high school-aged patients about alcohol use and to advise young people to reduce or stop drinking, according to a study led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. In a random survey of more than 2,500 10th grade students with an average age of 16...

Bill Lands
BILL LANDS Volunteer (Born: July 22, 1930, Chillicothe, Missouri) was Professor of Biochemistry in Medical Schools at the University of Michigan (1955-1980) and the University of Illinois (1980-1991) where he studied the metabolism of fats, phospholipids, and prostaglandins. He authored as Lands, WE (and recently as Lands, B) over 300 papers and the book, Fish, Omega-3 and Human Health, 2nd...
Molecule hijacks enzyme to boost alcohol metabolism
An experimental compound empowers an enzyme to help process acetaldehyde, a toxic metabolite of alcohol, according to new research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The findings, now online in the Proceedings of the National Academy of Sciences (PNAS), might lead to new treatments to help people with impaired ability to metabolize acetaldehyde and other...
NIAAA selects winners of its Wearable Alcohol Biosensor Challenge
$200,000 first prize awarded to BACtrack Skyn Today the National Institute on Alcohol Abuse and Alcoholism announced the winners of its Wearable Alcohol Biosensor Challenge, a competition to design a discreet device capable of measuring blood alcohol levels in near real-time. The winning prototype and recipient of the $200,000 first prize was submitted by BACtrack, a company known nationally for...
NIH study finds doctors miss many alcohol screening opportunities

Physicians often fail to counsel their young adult patients about excessive alcohol use, according to a study led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. NIAAA guidelines for low risk drinking call for men to drink no more than four drinks in a day and no more than 14 drinks...

Two NIH Institutes Share Emmy Award for HBOメs The Addiction Project

Two Institutes at the National Institutes of Health (NIH) have been honored with the prestigious Governors Award by the Academy of Television Arts and Sciences for their work with HBO on the Addiction Project. "Addiction" is a 14-part documentary television series and multimedia initiative revealing the science of addiction, its treatment, recovery, and its costs to families and society. A...

Smokers with Psychiatric Disorders including Nicotine Dependence Consume Most U.S. Cigarettes: Findings Raise Questions for Health Professionals, Researchers
Adults with nicotine dependence and/or psychiatric disorders consume 70 percent of all cigarettes smoked in the United States, according to results of a National Institutes of Health (NIH) study reported in the November issue of the Archives of General Psychiatry (Volume 61). Based on the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), the article provides the first...
NIH competition seeks wearable device to detect alcohol levels in real-time

NIAAA seeks innovative designs that use alternatives to measuring BAC through sweat The National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health, is once again challenging the biotech community to design a wearable device capable of measuring blood alcohol in near real-time. The ideal device would be capable of measuring alcohol concentration in the blood...

NIH begins clinical trial of new medication for alcohol use disorder

A clinical trial investigating a potential treatment for alcohol use disorder (AUD) was announced by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The study will assess the safety and efficacy of gabapentin enacarbil (HORIZANT) in extended-release tablets for treating moderate to severe AUD. NIAAA is part of the National Institutes of Health. Gabapentin is already widely prescribed to...

NIH study identifies gene variant linked to compulsive drinking
Carrying a gene variant that affects the release of a specific brain protein may put one at greater risk of developing an alcohol use disorder, according to the results of a recent animal study. The study was led by Professor Dorit Ron, PhD, Endowed Chair of Cell Biology of Addiction, Department of Neurology, University of California, San Francisco, and was...
NIH releases comprehensive resource to help address college drinking
CollegeAIM is a convenient, research-based tool for comparing college alcohol interventions CollegeAIM, a new resource to help college officials address harmful and underage student drinking, is now available. The CollegeAIM (Alcohol Intervention Matrix) guide and website was developed by the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health. The centerpiece of CollegeAIM is a...
New preclinical study points to potential role of human gene in addiction
A new study led by researchers at the National Institute and Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), identifies regions of the rat genome that are associated with a behavior that is highly predictive of addiction onset and progression. The region in the rat genome with the strongest association with the behavior corresponded to...
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