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Joint CRAN Advisory Council Agenda - May 3, 2017

DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM NATIONAL INSTITUTE ON DRUG ABUSE NATIONAL CANCER INSTITUTE AGENDA FIFTH JOINT MEETING (FOURTH CRAN) OF THE NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM, NATIONAL CANCER ADVISORY BOARD, AND THE NATIONAL ADVISORY COUNCIL ON DRUG ABUSE WEDNESDAY, MAY 3, 2017 Webcast: https://videocast.nih.gov/live.asp?live=21960 OPEN...

Gene variants predict treatment success for alcoholism medication

The effectiveness of an experimental treatment for alcoholism depends on the genetic makeup of individuals who receive it, according to a new study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. A report of the findings appears online in the American Journal of Psychiatry. “This study represents an important milestone...

COGA Genome Scan Suggests Linkage on Chromosomes 1, 2, 4, and 7

Washington, D.C. Theodore Reich, M.D., Department of Psychiatry, Washington University School of Medicine, St. Louis, and colleagues at that university and others in the NIAAA-supported Collaborative Study on the Genetics of Alcoholism (COGA) report in this month's Neuropsychiatric Genetics (Volume 81, Number 3) highly suggestive evidence on chromosomes 1 and 7 and more modest evidence on chromosome 2 for linkage...

Disclaimer

Endorsement and Liability Disclaimer The National Institute on Alcohol Abuse and Alcoholism (NIAAA) does not endorse or recommend any commercial products, processes, or services. The information on NIAAA's Web site may not be used for advertising or product endorsement purposes. The NIAAA website provides links to other Internet sites for informational purposes only. When users select a link to an...

The Right to Resist

When middle schoolers face pressure to do things that are not right or good for them, they have the right to resist. They have the right to say no, the right not to give a reason why, and the right to just walk away from a situation. Resisting pressure can be hard for some people. Why? They… Are afraid of...

Scientists find brain pathways for threat response in mice

This article was first published in NIAAA Spectrum Volume 16, Issue 2 . Scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) have identified brain pathways that may coordinate an animal’s response to potentially traumatic situations. Understanding where and how neural circuits mediate such functions—and how they could malfunction—may provide clues about their role in trauma-related and stress-related...

Office of the Clinical Director

Description The OCD’s main purposes are to ensure patient safety and confidentiality, monitor regulatory compliance, assist in policy and resource management, foster training and education, and facilitate the work of intramural clinical investigators. The specific functions of the OCD include: 1) Providing oversight of patient care and patient-related activities within the Division of Intramural Clinical and Biological Research (DICBR), including...

NIAAA policy for Submission of Applications Containing Genome-Wide Association Studies

NIAAA issued this notice NOT-AA-17-002 ( https://grants.nih.gov/grants/guide/notice-files/NOT-AA-17-002.html) to communicate the policy regarding grant applications seeking to identify common variants conferring genetic risks for alcohol use disorder (AUD) and related phenotypes. The policy is based on recommendations from the Genetics and Genomics Advisory Meeting NIAAA convened on October 26, 2016. The Advisory Panel determined that Genome-Wide Association Studies (GWAS) are currently...

Substance Abuse Prevention and Other Pregnancy Risk Studies

April 23-24, 1998 • Ramada Inn • Bethesda, Maryland Abstracts Substance Abuse in Pregnant Women Richard S. Schottenfeld, M.D. From the Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut The objective of this program was to evaluate the prevalence, patterns, and correlates of tobacco, alcohol, marijuana, and cocaine use during pregnancy in an urban hospital prenatal clinic...

Mary Kate Weber, CDC

Mary Kate Weber, M.P.H. Behavioral Scientist Prenatal Substance Exposure Surveillance and Research Team Infant Outcomes Monitoring, Research, and Prevention Branch Division of Birth Defects and Infant Disorders National Center on Birth Defects and Developmental Disabilities Centers for Disease Control and Prevention 4770 Buford Hwy, Mailstop S106-3 Atlanta, GA 30341 Phone: (404) 498-3926 Email: [email protected] Biographical Summary Mary Kate Weber, M.P.H...

Schedule of Scientific Review Group Meetings

FIRST LEVEL OF REVIEW OF GRANT APPLICATIONS AND COOPERATIVE AGREEMENTS: NIAAA Study Sections: Biomedical Research Study Section (AA-1) SRO: Mamatha Garige, Ph.D. (301) 443-9737 Meeting Dates & Roster, go to AA-1 Committee Roster Epidemiology, Prevention and Behavior Research Study Section (AA-2) SRO: Anna Ghambaryan, M.D., Ph.D. (301) 443-4032 Meeting Dates & Roster, go to AA-2 Committee Roster Clinical, Treatment and...

A New Treatment Strategy for Alcohol-Associated Liver Disease

Alcohol is involved in nearly half of all liver disease deaths in the United States each year. Alcohol-associated liver disease (AALD) now replaces hepatitis C viral infection as the lead cause of liver transplantation due to chronic liver disease. Consequently, there is an urgent need for effective interventions for AALD, a complex disease with multiple contributing factors. One of these...

Landmark Survey Reports the Prevalence of Personality Disorders in the United States

An estimated 30.8 million American adults (14.8 percent) meet standard diagnostic criteria for at least one personality disorder as defined in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV), according to the results of the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) reported in the current issue of the Journal of Clinical...

Dr. Markus Heilig Named NIAAA Clinical Director

National Institute on Alcohol Abuse and Alcoholism (NIAAA) Director Ting-Kai Li, M.D., has named Markus Heilig, M.D., Ph.D., as Chief of the Laboratory of Clinical Studies (LCS), and Clinical Director in NIAAA's Division of Intramural Clinical and Biological Research. "We are fortunate to have Dr. Heilig in these important positions," says Dr. Li. "He is an outstanding clinician and a...

Special Emphasis Panels

Special Emphasis Panels (SEPs) have been established by NIH Institutes, Centers and Divisions to cover all scientific peer review activities formerly provided by ad hoc groups. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) has established a chartered SEP to provide concept review of proposed contract or grant solicitations and to review grant and cooperative agreement applications and contract...

Research Training & Career Development Opportunities by Grant Mechanism

Opportunities by Education Level Key to understanding the complex world of NIH Funding is mastering the different types of funding mechanisms. This page provides information on the different training and career development grants broken out by their funding mechanism (K, F or T). The information below is focused on NIH training programs in which the National Institute on Alcohol Abuse...

Research Training & Career Development Opportunities by Education Level

Opportunities by Grant Mechanism Navigating the complex world of NIH Funding can be daunting. Hopefully these pages will help you to better understand your eligibility for various grants and programs based on your specific education level. The information below is focused on NIH training programs in which the National Institute on Alcohol Abuse and Alcoholism (NIAAA) participates. Links are provided...

NIAAA Spectrum: Brain Scans Reveal Heavy Drinking Damages White Matter

Researchers led by Catherine Fortier at Harvard Medical School found that chronic alcohol misuse damaged white matter in areas of the brain that are important for self-control and recovery from alcoholism. The findings appeared in the December 2014 issue of Alcoholism: Clinical & Experimental Research. Using high-resolution diffusion magnetic resonance brain scans, the researchers compared a group of 20 healthy...

NIAAA COVID-19 Notice of Special Interest (NOSI) and Other NIH Funding Opportunities

NIAAA has issued a Notice of Special Interest (NOSI) for administrative supplements and competitive revisions focused on urgent research questions of significance to alcohol and the COVID-19 pandemic ( NOT-AA-20-11). NIAAA is also participating in other NIH NOSIs and funding opportunities focused on COVID-19 research questions. These NOSIs are linked to PA-18-591 (administrative supplement) and PA-18-935 (urgent competitive revision). Administrative...

Researchers Identify Potential Medication for Early-Onset Alcoholism -- Findings advance search for mechanisms of disease--

Investigators at the University of Texas Health Science Center at San Antonio report in the lead article in today's Journal of the American Medical Association (Volume 284, Number 8) that the medication ondansetron may be an effective therapy for patients with early-onset alcohol dependence (alcoholism). Ondansetron appears to work by acting on serotonin, one of the brain's many neurotransmitters. The...

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