Mission Statement: The mission of the Laboratory of Liver Diseases is to investigate the immunological aspects and molecular pathogenesis of alcoholic and nonalcoholic fatty liver diseases, and to explore novel therapeutic targets for the treatment of these disorders. Bin Gao MD. , PhD, Chief Laboratory of Liver Diseases National Institute on Alcohol Abuse and Alcoholism National Institutes of Health 5625...

This is a correction to the webex connection information for the ABCD pre-application technical assistance webinar, which will be conducted on Tuesday, February 24, 2015 from 1:00 to 2:30 p.m. EST to discuss the three new Adolescent Brain Cognitive Development (ABCD) Longitudinal Study funding opportunities: (1) a set of research project sites ( RFA-DA-15-015), (2) a single central data analysis...

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) requires enhanced monitoring and reporting for NIAAA-supported clinical trials that are rated as greater than minimal risk (as defined in federal regulations at 45 CFR 46.102(i) and 21 CFR 50.3(k)). The purpose of this guidance document is to clarify risk level definitions and NIAAA’s monitoring and reporting expectations for all NIAAA-funded...

NIDA, NIAAA, and NCI announce the release of 2 new NOFOs to promote the goals of Collaborative Research on Addiction at NIH (CRAN; formerly known as functional integration). Its mission is to provide a strong collaborative framework for enabling NIDA, NIAAA, and NCI to pool resources and expertise, creating synergies in addiction science, addressing new research opportunities, and meeting the...

November 11, 2016, 8:30am - 5:30pm San Diego Convention Center, Room 7; San Diego, California Visit the Web site Summary The theme of this year’s mini-convention is on relapse and recovery, with an emphasis on integration of preclinical and clinical research and leveraging insights from big data approaches. The symposium will highlight notable studies in drug and alcohol research, in...

The NIAAA has joined the Center for Inherited Disease Research (CIDR) to assist investigators who are currently conducting, or who have an interest in initiating studies to identify genes that contribute to alcoholism and alcohol-related disorders. The CIDR provides a variety of genotyping and statistical genetics services for both human and animal studies to identify genes that contribute to human...

Introduction This guidance is intended to assist the National Institute on Alcohol Abuse and Alcoholism (NIAAA)-supported extramural researchers in establishing and operating a Data and Safety Monitoring Board (DSMB) for clinical trials [1] funded by NIAAA. The purpose of the DSMB is to provide oversight and monitoring of the conduct of clinical trials to ensure the safety of participants and...

George Kunos MD. , PhD. Chief National Institute on Alcohol Abuse and Alcoholism National Institutes of Health 5625 Fishers Lane, Room 2S-24:MSC 9413 Bethesda MD 20892-9413 telephone: +1 301.443.2069 fax: +1 301.480.0257 e-mail: [email protected] Mission Statement The Biology and Functions of the Endocannabinoid System Endocannabinoids are lipid-like mediators discovered in the 1 990s that bind to cannabinoid receptors to trigger...

NIH-funded study provides hope for noninvasive detection of early liver disease. What: A new compound that binds to, and enables MRI imaging of, liver cells in the early stage of disease, has been developed by scientists supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the NIH. Researchers report that, in imaging studies of animal models...

The National Institute on Alcohol Abuse and Alcoholism sadly announces the death of Richard L. Veech, MD, DPhil, Chief of the NIAAA Laboratory of Metabolic Control. Dr. Veech joined NIH after earning his bachelor’s and medical degrees at Harvard and his DPhil at Oxford under the tutelage of Hans Krebs. While in the process of completing his graduate work at...

NIH-supported, multi-institute research program will generate robust data about how young brains mature. With nearly $290M of new funding for seven years to research institutions around the country, the National Institutes of Health renewed its commitment to the Adolescent Brain Cognitive Development (ABCD) Study, the largest long-term study of brain development and child health ever conducted in the United States...

Drinking may harm adolescents' ability to concentrate and to understand spatial relationships. A recent study led by Susan Tapert at the University of California, San Diego compared the standardized test scores of 76 12 to 14 year old kids with their scores after about three years. At the three-year follow-up, 36 of the kids had begun drinking at moderate to...

Xin Jin, Ph.D., a postdoctoral fellow at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health, received the Peter and Patricia Gruber International Research Award from the Society for Neuroscience today during the society’s annual meeting in Washington, D.C. The $25,000 prize is awarded annually to two young scientists whose research includes significant...

Recent research from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) sheds new light on habitual behaviors, specifically the circuits in the brain that allow mice to break from routine actions. Such shifting between old habits and new behavior aimed at accomplishing a particular goal are critical to flexible decision-making in everyday life. It also has important implications for...

Yu-Hong Lin, Ph.D. Staff Scientist Telephone: +1 301.443.9031 Fax: +1 301.594.0035 e-mail: [email protected] Dr. Lin’s research focuses on understanding the effect of dietary fat on the metabolism of essential fatty acids in vivo and in vitro employing stable isotope tracer techniques coupled with gas chromatography/ mass spectrometry. She examines both humans and animals with physiological and pathophysiological conditions such as...

Administrative supplement applications submitted in response to the NIH Notice of Funding Opportunity (NOFO) PA-20-272, Administrative Supplements to Existing NIH Grants and Cooperative Agreements (parent administrative supplement NOFO). NIAAA may accept unsolicited administrative supplement applications submitted through PA-20-272, or linked to a notice of special interests (NOSI), which must be indicated in Box4B of the application. Timeline Unless otherwise specified...

April 23-24, 1998 • Ramada Inn • Bethesda, Maryland Abstracts Meta-Analysis of Validated Cessation in Randomized Controlled Trials Patricia Dolan Mullen, Dr.P.H. From the Center for Health Promotion Research and Development, University of Texas-Houston School of Public Health, Houston, Texas Of more than 30 reports of findings from evaluations of pregnancy smoking cessation interventions (PSC) in "developed" countries, 16 were...

알코올은 뇌의 의사소통 경로를 방해하고 뇌가 보고 작용하는 방식에 영향을 미칠 수 있습니다. 알코올은 균형, 기억, 언어 및 판단을 제어하는 뇌 영역이 작용하기가 어려워지게 하며, 부상 및 기타 부정적인 결과가 발생할 가능성을 높아지게 합니다. 장기적 과음은 뉴런 크기 감소와 같은 뉴런의 변화를 유발합니다. 다음은 알코올 및 뇌와 관련된 몇 가지 주요 주제입니다. 청소년 뇌 청소년 뇌는 성인 뇌보다 알코올의 부정적인...

Background: Scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) led by CAPT Joseph R. Hibbeln, M.D., teamed with researchers at the Uniformed Services University of the Health Sciences (USUHS) in Bethesda, Md., to analyze a sample of suicide deaths among U.S. military personnel on active duty between 2002 and 2008. The researchers compared levels of omega-3 fatty...

Voluntary movements involve the coordinated activation of two brain pathways that connect parts of deep brain structures called the basal ganglia, according to a study in mice by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. The findings, which challenge the classical view of basal ganglia function, were published online...