Cinar, J. K. Park, C. N. Zawatsky, N.J. Coffey, S. P. Bodine, J. Abdalla, T.Yokoyama, T. Jourdan, L.Jay, M. X. G. Zuo, K. J. O’Brien, J.Huang, K. Mackie, A.Alimardanov, M.R. Iyer, W. A. Gahl, G. Kunos, B. R. Gochuico, M. C. V. Malicdan. (2021) CB1R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky-Pudlak syndrome. Clin. and Transl. Med. 2021, 11: e471.
Z.Liu, M. R. Iyer, G. Godlewski, T. Jourdan, J. Liu, N. J. Coffey, C. N. Zawatsky, H. L. Puhl, J. Wess, J. Meister, J.-S. Liow, R. B. Innis, S. A. Hassan, Y. S. Lee, G. Kunos, and R. Cinar (2021) Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB1R) Antagonist. ACS Pharmacol. & Transl. Sci., 4(3):1175-1187.
Zawatsky CN, Abdalla J, Cinar R. (2020) Synthetic cannabinoids induce acute lung inflammation via cannabinoid 1 activation. ERJ Open Research 6(3):00121.
J.K. Park, N. J. Coffey, S.P. Bodine, C. N. Zawatsky, L. Jay, W. A. Gahl, G. Kunos, B. R. Gochuico, M. C. V. Malicdan, R Cinar. (2020) Bleomycin induce drug efflux in lung: a pitfal for pharmacological studies in pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology- 62(2): 178-190.
Cinar, B. Gochuico, M.R. Iyer, T. Jourdan, T. Yokoyama, J. K. Park, N. Coffey, H. Pri-Chen, G. Szanda, Z. Liu, W. Gahl, G. Kunos (2017) Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis. JCI Insight 2(8):92281.
Cinar, M. R. Iyer, Z. Liu, Z. Cao, T. Jourdan, K. Erdelyi, G. Godlewski, G. Szanda, J. Liu, J. K. Park, B. Mukhopadhyay, A.Z. Rosenberg, J.S. Liow, R. G. Lorenz, P. Pacher, R. B. Innis, G. Kunos. (2016) Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis. JCI Insight 1(11): e87336.
Reviews
Cinar R, MR Iyer, G Kunos. (2021) Dual inhibition of Cb1 receptors and iNOS, as a potential novel approach to the pharmacological management of acute and long COVID-19. Br J. Pharmacol doi.org/10.1111/bph.15461.
Cinar, M.R. Iyer, G. Kunos. (2020) The therapeutic potential of second and third generation CB1R antagonists. Pharmacology and Therapeutics, 208:107477.
Patents
G Kunos , M Iyer , R Cinar , KC Rice , inventors; The United States of America as represented by the Department of Health and Human Services, assignee. Cannabinoid receptor mediating compounds. United States patent US 9,765,031. 19 Sep 2017.
G Kunos , M Iyer , R Cinar , KC Rice inventors; The United States of America as represented by the Department of Health and Human Services, assignee. Pyrazole derivatives and their use as cannabinoid receptor mediators United States patent US 10,329,259. 25 Jun 2019.
G Kunos , M Iyer , R Cinar , KC Rice, inventors; The United States of America as represented by the Department of Health and Human Services, assignee. Cannabinoid receptor mediating compounds. United States patent US 10,683,270. 16 Jun 2020.
G Kunos , M Iyer , R Cinar , KC Rice, inventors; The United States of America as represented by the Department of Health and Human Services, assignee. Cannabinoid receptor mediating iminopyrazole compounds. United States patent US 10,787,419. 29 Sep 2020.
R Cinar, G Kunos , M.R. Iyer , W. A. Gahl, B.R. Gochuico, M.C.V. Malicdan, inventors; The United States of America as represented by the Department of Health and Human Services, assignee. Cannabinoid receptor mediating compounds. United States patent US 11,155,521. 26 Oct 2021.
