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A clinical trial investigating a potential treatment for alcohol use disorder (AUD) was announced by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The study will assess the safety and efficacy of gabapentin enacarbil (HORIZANT) in extended-release tablets for treating moderate to severe AUD. NIAAA is part of the National Institutes of Health. Gabapentin is already widely prescribed to...
Home General Info Agenda Accommodations and Logistics Contact Registration Recommended Reading Our Sponsors 2017 National Conference on Alcohol and Opioid Use in Women & Girls: Advances in Prevention, Treatment and Recovery Research October 26 - 27, 2017 Washington Marriott at Metro Center Washington, DC As a follow-up to the 2008 National Conference on Preventing Substance-exposed Pregnancies sponsored by the ICCFASD...
The NIAAA Jack Mendelson Honorary Lecture will take place as a virtual event on Septermber 22, 2020. This year's presenter is Dr. Sandra A. Brown, Vice Chancellor for Research and distinguished Professor of Psychology and Psychiatry at the University of California San Diego ( UCSD). The title of her presentation is " Discerning Risks and Effects of Alcohol in the...
Bernice Porjesz, Ph.D., Department of Psychiatry, State University of New York, Health Sciences Center at Brooklyn, and others from six of the nine universities that comprise NIAAA's Collaborative Study of the Genetics of Alcoholism (COGA) report in today's online version of the Proceedings of the National Academy of Sciences (99[6]:3729-3733) significant linkage and linkage disequilibrium between beta brain wave (EEG)...
Recent research suggests that receptors for the neurotransmitter GABA(A) that lie outside of the synapse and which contain a molecular fragment known as a delta-subunit are sensitive to alcohol, raising the possibility that these receptors might help produce alcohol’s reinforcing effects after consuming one or a few drinks. In the current study, researchers tested the hypothesis that these extrasynaptic GABA(A)...
NIH researchers seek to expand treatment options The National Institute on Alcohol Abuse and Alcoholism (NIAAA) will conduct a clinical trial of gabapentin enacarbil as a potential treatment for alcohol use disorder (AUD). NIAAA estimates that the six-month trial will begin in the first half of 2015 and will enroll approximately 350 participants. The study will assess the safety and...
New research supported by the National Institutes of Health shows how elements of the brain’s stress and reward pathways can interact to suppress binge alcohol drinking. The finding, now online in the journal Nature Neuroscience, suggests potential strategies for treating and preventing alcohol use problems. “This study is an important contribution to our knowledge of the neurobiology of alcohol use...
At some time during their lives, more than 30 percent of U.S. adults surveyed in 2001-2002 had met current diagnostic criteria [i] for an alcohol use disorder (AUD), according to an article in the current issue of the Archives of General Psychiatry. Many of those persons never received treatment, and many others did not receive treatment until well after AUD...
Scientists tracking the progress of children diagnosed with attention-deficit/hyperactivity disorder (ADHD) as they became teenagers have shed new light on the link between ADHD and the risk of developing alcohol and substance use problems. The researchers found that individuals with severe problems of inattention as children were more likely than their peers to report alcohol-related problems, a greater frequency of...
