National Institute on Alcohol Abuse and Alcoholism (NIAAA)

DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM NATIONAL INSTITUTE ON DRUG ABUSE NATIONAL CANCER INSTITUTE AGENDA EIGHTH JOINT MEETING (SEVENTH CRAN) OF THE NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM, NATIONAL CANCER ADVISORY BOARD AND THE NATIONAL ADVISORY COUNCIL ON DRUG ABUSE WEDNESDAY, May 13, 2020 11:30 AM –...

Administrative supplement applications submitted in response to the NIH Notice of Funding Opportunity (NOFO) PA-20-272, Administrative Supplements to Existing NIH Grants and Cooperative Agreements (parent administrative supplement NOFO). NIAAA may accept unsolicited administrative supplement applications submitted through PA-20-272, or linked to a notice of special interests (NOSI), which must be indicated in Box4B of the application. Timeline Unless otherwise specified...

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) will be hosting a Twitter Chat, “Alcohol & the Holidays: What You Need to Know.” The chat will cover tips for celebrating the season safely if you choose to drink, vital stats about drunk driving, and evidence-based advice for those thinking about reducing their drinking in the New Year. The chat...

DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM NATIONAL INSTITUTE ON DRUG ABUSE NATIONAL CANCER INSTITUTE AGENDA 4th Joint Meeting of the NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM, NATIONAL CANCER ADVISORY BOARD, AND THE NATIONAL ADVISORY COUNCIL ON DRUG ABUSE February 11, 2016 Webcast: http://videocast.nih.gov/summary.asp?live=17886 OPEN TO THE PUBLIC...

The Research Society on Alcoholism ( RSA) has selected David Goldman, M.D., of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to receive the Distinguished Researcher Award. This award recognizes a senior researcher who, through sustained, long-term commitment to conducting alcohol research, has made outstanding scientific contributions to the field. Dr. Goldman is chief of the Laboratory of Neurogenetics...

DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM AGENDA 131th Meeting of the NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM September 19-20, 2012 Wednesday, September 19, 2012, 5:30 to 7:00 PM. 5635 Fishers Lane Terrace Level Conference Room Rockville, MD 20852 CLOSED TO THE PUBLIC 5:30 REVIEW OF GRANT APPLICATIONS...

Download PDF (396 KB) If you've ever needed a magnetic resonance imaging (MRI) scan, you may have had a contrast dye injected to create a clearer image. While MRI technology has improved greatly since its introduction in 1977, contrast dyes and the images they help produce have remained the same. InLighta BioSciences, a company supported through the National Institute on...

I feel compelled to address what we’ve seen and heard in the news regarding racism, police brutality, and injustice against African Americans in our country. I am outraged, horrified, and disillusioned—and I suspect most of you are, too. The effects are pervasive and touch all aspects of society. In addition, the COVID-19 pandemic has shown a bright light on the adverse impact of health inequities on African-American communities.

NIAAA SBIR and STTR Factsheet (PDF, 1,355 KB) About NIAAA's Small Business Research Funding Programs NIAAA’s Small Business Innovation Research (SBIR) & Small Business Technology Transfer Research (STTR) programs provide small businesses with funding and resources including grants, contracts, and technical support to explore and create new solutions for alcohol use disorder (AUD). SBIR supports early-stage research and development projects...

Approximately 10.5% (7.5 million) of U.S. children ages 17 and younger live with a parent who has alcohol use disorder, according to a 2017 report by the Substance Abuse and Mental Health Services Administration (SAMHSA). 1

DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM AGENDA 134th Meeting of the NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM September 18-19, 2013 Wednesday, September 18, 2013, 5:30 to 7:00 PM. 5635 Fishers Lane Terrace Level Conference Room Rockville MD 20852 CLOSED TO THE PUBLIC 5:30 REVIEW OF GRANT APPLICATIONS/MERIT...

Recent NIH-wide efforts to address sex differences in preclinical research underscore the importance of such issues to scientists who study alcohol addiction. “In fact, animal models of alcohol addiction reveal significant differences between males and females,” says NIAAA Director George F. Koob, Ph.D., “but we have little data thus far to help us understand the neurobiological mechanisms for those differences.”...

お酒を飲むと、アルコールが脳の情報を伝える経路を妨害して、脳の外観や働き方に影響を与えることがあります。アルコールは、脳の領域が平衡感覚を保ったり、記憶や発話、脳の働きの判断を統制したりするのを困難にします。すると、けがや良くない他の結果を招いてしまう可能性が高くなります。長期にわたる大量飲酒は、サイズの減少など神経細胞に変化を引き起こします。以下に、アルコールと脳に関する重要なトピックをいくつか示します。 青年期の脳 青年期の脳は、成人の脳よりもアルコールの悪影響を受けやすくなっています。青年期の大量飲酒は、脳の発達を変化させ、脳の構造と機能が長期的に変化してしまう可能性があります。 アルコールによる記憶喪失 大量飲酒は、 アルコールによる記憶喪失を引き起こす可能性があります。アルコールによる記憶喪失とは、酔っている間に起きた出来事を覚えていない記憶の空白時間があることです。記憶の空白が起こるのは、記憶を短い間保存するところから、長い間保存するところへ転送（記憶の固定化として、知られています）するのを一時的に阻害するほどのアルコールを飲んだときです。この働きをする脳の領域は、海馬と呼ばれています。 アルコールの過剰摂取 かなりの障害があることをはっきりと示す徴候があるのに飲酒を続けてしまうと、 アルコールの過剰摂取になることがあります。アルコール過剰摂取は、血流中にアルコールがたくさんある場合に起こり、呼吸、心拍数、および体温管理などの基本的生命維持機能をコンロトールしている脳の領域が機能停止し始めます。アルコール過剰摂取の症状には、精神錯乱、意識維持困難、嘔吐、発作、呼吸困難、心拍数の低下、冷たくて湿っぽい肌、反応の鈍化（窒息を防ぐ咽頭反射がないなど）、および体温の極端な低下などがあります。アルコールを過剰摂取すると、脳の永続的な損傷や死亡に至る場合があります。 アルコール使用障害 お酒を飲み続けるにつれて、脳の構造や機能に進行性の変化が起こることがあります。これらの変化で脳の機能が損なわれてしまい、飲酒は時々で酒量もほどほどだったところから、絶えず大量に飲酒するようになる可能性があります。そうなると、制御するのが難しく、 アルコール使用障害に至ることがあります。中等度から重度のアルコール使用障害の方は、 アルコール依存症のサイクルに入り込む可能性があります。長期の断酒後に、脳がどの程度正常に戻るかは完全には解明されていません。しかし、少なくともアルコール使用障害による一部の脳の変化や、それに伴う思考、感情、行動の変化は、数ヵ月の禁酒によって改善し、回復する可能性を示す研究が増えつつあります。［アルコール使用障害の神経科学に関する詳細については、ア ルコールに関する医療従事者のコアリソース（The Healthcare Professional’s Core Resource on Alcohol）の 神経科学：依存症と回復における脳（Neuroscience: The Brain in Addiction and Recovery）の項をご覧ください］。 出生前のアルコール曝露 出生前のアルコール曝露は脳の損傷を引き起こす可能性があり、小児期のいずれかの時点で発達、認知、行動に関するさまざまな問題を引き起こす可能性があります。アルコールは、妊娠期間中のどの段階でも胎児の発育を妨げる可能性があります。この期間には、妊娠初期や女性が妊娠に気づく前の時期も含まれます。 アルコールと脳の健康についての詳細については、 お酒（アルコール）と脳についてのトピックページをご覧ください。

Finding has implications for alcoholism and other patterns of addictive behavior Research from the National Institutes of Health has identified neural circuits in mice that are involved in the ability to learn and alter behaviors. The findings help to explain the brain processes that govern choice and the ability to adapt behavior based on the end results. Researchers think this...

Breakthrough findings could lead to more effective prevention and treatment strategies for multiple substance use disorders By combing through genomic data of over 1 million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used. This dataset – one of the largest of its kind – may help reveal new treatment targets across multiple...

Many children adversely affected by maternal drinking during pregnancy cannot be identified early in life using current diagnostic criteria for fetal alcohol spectrum disorder (FASD). In the current study, conducted with pregnant rats, researchers examined whether ethanol-induced alterations in placental gene expression may be useful as diagnostic indicators of maternal drinking during pregnancy and as a prognostic indicators of risk...

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This strategic plan includes four major goals, which cover the depth and breadth of research necessary to improve the understanding of and to address the effects of alcohol misuse on individuals and society. These goals complement the Cross-Cutting Research Themes, Cross-Cutting Research Programs, and Supporting the Mission sections of this strategic plan.